MECHANISMDefinition: sourced draft

Energy buffering

Supports the creatine–phosphocreatine system in tissue energy metabolism.

Mechanistic context

Creatine · Sourced draft

Energy buffering

Creatine availability supports the phosphocreatine system, which helps regenerate ATP during demanding activity. Source

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Linked substances

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Tagged articles and participants in the relationships above. A shared tag alone does not establish a causal effect.

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Definition sources

Supporting reading for this original editorial definition. Independent editorial review has not been recorded.

Observation & claim sources

  1. Position stand / review · 2017

    International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine

    Kreider et al.

    Summarizes muscle energy metabolism and exercise supplementation research.

    Limitation A professional-society position stand, not an independent trial; proposed clinical uses vary in evidence strength.

    Funding / disclosures Not assessed; consult the original disclosure.

    Source in Creatine