SUBJECTIVE EFFECTDefinition: sourced draft

Drowsiness

A subjective tendency toward sleep. Reports of drowsiness and laboratory performance can diverge.

Reported experience

1 observations

These qualitative descriptions preserve the reported direction and setting. They do not assign a universal intensity score.

DiphenhydramineSourced draft
Variable

Self-rated sedation

No significant difference from placebo was detected at this study exposure. This does not negate sedation warnings for the medicine. Source

Evidence type
Human research
Population
Younger and older healthy volunteers
Exposure
Single 25 mg oral exposure
Instrument
Self-ratings of sedation
Reported magnitude
Not established

Connections & claims

Open graph

Each relationship keeps its participants and their roles together. Source details explain what the connection supports.

No sourced relationships have been assessed for this concept yet.

Linked substances

1 entries

Tagged articles and participants in the relationships above. A shared tag alone does not establish a causal effect.

Follow the sources

Definition sources

Supporting reading for this original editorial definition. Independent editorial review has not been recorded.

Observation & claim sources

  1. Randomized placebo-controlled crossover study · 1998

    Pharmacokinetics and pharmacodynamics of diphenhydramine 25 mg in young and elderly volunteers

    Scavone et al.

    Did not detect significant age effects on kinetics or sedation differences at the tested exposure.

    Limitation An undetected difference in one acute experiment does not establish absence of impairment in other settings.

    Funding / disclosures NIMH support is listed in the PubMed record; other funding not assessed.

    Source in Diphenhydramine