SUBJECTIVE EFFECTDefinition: sourced draft
Drowsiness
A subjective tendency toward sleep. Reports of drowsiness and laboratory performance can diverge.
Reported experience
1 observationsThese qualitative descriptions preserve the reported direction and setting. They do not assign a universal intensity score.
Self-rated sedation
No significant difference from placebo was detected at this study exposure. This does not negate sedation warnings for the medicine. Source
- Evidence type
- Human research
- Population
- Younger and older healthy volunteers
- Exposure
- Single 25 mg oral exposure
- Instrument
- Self-ratings of sedation
- Reported magnitude
- Not established
Each relationship keeps its participants and their roles together. Source details explain what the connection supports.
No sourced relationships have been assessed for this concept yet.
Linked substances
1 entriesTagged articles and participants in the relationships above. A shared tag alone does not establish a causal effect.
Follow the sources
Definition sources
Supporting reading for this original editorial definition. Independent editorial review has not been recorded.
Observation & claim sources
- Randomized placebo-controlled crossover study · 1998Scavone et al.
Did not detect significant age effects on kinetics or sedation differences at the tested exposure.
Limitation An undetected difference in one acute experiment does not establish absence of impairment in other settings.
Funding / disclosures NIMH support is listed in the PubMed record; other funding not assessed.
Source in Diphenhydramine